Oral Verruciform Xanthoma: A Case Report and Literature Review
Identifieur interne : 003331 ( Main/Exploration ); précédent : 003330; suivant : 003332Oral Verruciform Xanthoma: A Case Report and Literature Review
Auteurs : Akshay Shetty [Inde] ; Kourosh Nakhaei [Inde] ; Yogesh Lakkashetty [Inde] ; Maryam Mohseni [Inde] ; Iman Mohebatzadeh [Inde]Source :
- Case Reports in Dentistry [ 2090-6447 ] ; 2013.
Abstract
Verruciform xanthoma is a benign mucocutaneous, uncommon, nonsymptomatic lesion of uncertain etiopathology, which occurs mostly on the oral mucosa of middle-aged individuals. Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue. A 60-year-old male patient presented with a painless growth on the left buccal mucosa. On clinical examination a yellowish white exophytic lesion, measuring 11 × 7 mm in size, was found, which was cauliflower-shaped on inspection and painless on palpation. Histopathological examination revealed varying degrees of surface parakeratosis and the accumulation of numerous foam cells in the connective tissue papillae among the uniformly elongated epithelial ridges. On immunohistochemical staining, there was a neutrophilic infiltrate of the epidermis with CD68 positive xanthoma cells restricted to the papillary dermis, mixed with other chronic inflammatory cells.
Url:
DOI: 10.1155/2013/528967
PubMed: 24396610
PubMed Central: 3876769
Affiliations:
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sortKey="Nakhaei, Kourosh" sort="Nakhaei, Kourosh" uniqKey="Nakhaei K" first="Kourosh" last="Nakhaei">Kourosh Nakhaei</name><affiliation wicri:level="1"><nlm:aff id="I2">Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032</wicri:regionArea><wicri:noRegion>Bangalore 560032</wicri:noRegion></affiliation></author><author><name sortKey="Lakkashetty, Yogesh" sort="Lakkashetty, Yogesh" uniqKey="Lakkashetty Y" first="Yogesh" last="Lakkashetty">Yogesh Lakkashetty</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Oral and Maxillofacial Pathology, Sri Rajiv 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560032, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, RT Nagar, Bangalore 560032</wicri:regionArea><wicri:noRegion>Bangalore 560032</wicri:noRegion></affiliation></author></analytic><series><title level="j">Case Reports in Dentistry</title><idno type="ISSN">2090-6447</idno><idno type="eISSN">2090-6455</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Verruciform xanthoma is a benign mucocutaneous, uncommon, nonsymptomatic lesion of uncertain etiopathology, which occurs mostly on the oral mucosa of middle-aged individuals. Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue. A 60-year-old male patient presented with a painless growth on the left buccal mucosa. On clinical examination a yellowish white exophytic lesion, measuring 11 × 7 mm in size, was found, which was cauliflower-shaped on inspection and painless on palpation. Histopathological examination revealed varying degrees of surface parakeratosis and the accumulation of numerous foam cells in the connective tissue papillae among the uniformly elongated epithelial ridges. On immunohistochemical staining, there was a neutrophilic infiltrate of the epidermis with CD68 positive xanthoma cells restricted to the papillary dermis, mixed with other chronic inflammatory cells.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Mohsin, Sk" uniqKey="Mohsin S">SK Mohsin</name></author><author><name sortKey="Lee, Mw" uniqKey="Lee M">MW Lee</name></author><author><name sortKey="Amin, Mb" uniqKey="Amin M">MB Amin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajendran, R" uniqKey="Rajendran R">R Rajendran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buchner, A" uniqKey="Buchner A">A Buchner</name></author><author><name sortKey="Hansen, Ls" uniqKey="Hansen L">LS Hansen</name></author><author><name sortKey="Merrell, Pw" uniqKey="Merrell P">PW Merrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shafer, 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sortKey="Lakkashetty, Yogesh" sort="Lakkashetty, Yogesh" uniqKey="Lakkashetty Y" first="Yogesh" last="Lakkashetty">Yogesh Lakkashetty</name><name sortKey="Mohebatzadeh, Iman" sort="Mohebatzadeh, Iman" uniqKey="Mohebatzadeh I" first="Iman" last="Mohebatzadeh">Iman Mohebatzadeh</name><name sortKey="Mohseni, Maryam" sort="Mohseni, Maryam" uniqKey="Mohseni M" first="Maryam" last="Mohseni">Maryam Mohseni</name><name sortKey="Nakhaei, Kourosh" sort="Nakhaei, Kourosh" uniqKey="Nakhaei K" first="Kourosh" last="Nakhaei">Kourosh Nakhaei</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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